foregone dinner: May 2012

Thursday, May 31, 2012

In Thailand, Suu Kyi vows to help Myanmar migrants

[ [ [['Connery is an experienced stuntman', 2]], 'http://yhoo.it/KeQd0p', '[Slideshow: See photos taken on the way down]', ' ', '630', ' ', ' ', ], [ [['Connery is an experienced stuntman', 7]], ' http://yhoo.it/KpUoHO', '[Slideshow: Death-defying daredevils]', ' ', '630', ' ', ' ', ], [ [['know that we have confidence in', 3]], 'http://yhoo.it/LqYjAX ', '[Related: The Secret Service guide to Cartagena]', ' ', '630', ' ', ' ', ], [ [['We picked up this other dog and', 5]], 'http://yhoo.it/JUSxvi', '[Related: 8 common dog fears, how to calm them]', ' ', '630', ' ', ' ', ], [ [['accused of running a fake hepatitis B', 5]], 'http://bit.ly/JnoJYN', '[Related: Did WH share raid details with filmmakers?]', ' ', '630', ' ', ' ', ], [ [['accused of running a fake hepatitis B', 3]], 'http://bit.ly/KoKiqJ', '[Factbox: AQAP, al-Qaeda in Yemen]', ' ', '630', ' ', ' ', ], [ [['have my contacts on or glasses', 3]], 'http://abcn.ws/KTE5AZ', '[Related: Should the murder charge be dropped?]', ' ', '630', ' ', ' ', ], [ [['have made this nation great as Sarah Palin', 5]], 'http://yhoo.it/JD7nlD', '[Related: Bristol Palin reality show debuts June 19]', ' ', '630', ' ', ' ', ], [ [['have made this nation great as Sarah Palin', 1]], 'http://bit.ly/JRPFRO', '[Related: McCain adviser who vetted Palin weighs in on VP race]', ' ', '630', ' ', ' ', ], [ [['A JetBlue flight from New York to Las Vegas', 3]], 'http://yhoo.it/GV9zpj', '[Related: View photos of the JetBlue plane in Amarillo]', ' ', '630', ' ', ' ', ], [ [['the 28-year-old neighborhood watchman who shot and killed', 15]], 'http://news.yahoo.com/photos/white-house-stays-out-of-teen-s-killing-slideshow/', 'Click image to see more photos', 'http://l.yimg.com/cv/ip/ap/default/120411/martinzimmermen.jpg', '630', ' ', 'AP', ], [ [['Titanic', 7]], 'http://news.yahoo.com/titanic-anniversary/', ' ', 'http://l.yimg.com/a/p/us/news/editorial/b/4e/b4e5ad9f00b5dfeeec2226d53e173569.jpeg', '550', ' ', ' ', ], [ [['He was in shock and still strapped to his seat', 6]], 'http://news.yahoo.com/photos/navy-jet-crashes-in-virginia-slideshow/', 'Click image to see more photos', 'http://l.yimg.com/cv/ip/ap/default/120406/jet_ap.jpg', '630', ' ', 'AP', ], [ [['xxxxxxxxxxxx', 11]], 'http://news.yahoo.com/photos/russian-grannies-win-bid-to-sing-at-eurovision-1331223625-slideshow/', 'Click image to see more photos', 'http://l.yimg.com/a/p/us/news/editorial/1/56/156d92f2760dcd3e75bcd649a8b85fcf.jpeg', '500', ' ', 'AP', ] ]

[ [ [['did not go as far his colleague', 8]], '29438204', '0' ], [ [[' the 28-year-old neighborhood watchman who shot and killed', 4]], '28924649', '0' ], [ [['because I know God protects me', 14], ['Brian Snow was at a nearby credit union', 5]], '28811216', '0' ], [ [['The state news agency RIA-Novosti quoted Rosaviatsiya', 6]], '28805461', '0' ], [ [['measure all but certain to fail in the face of bipartisan', 4]], '28771014', '0' ], [ [['matter what you do in this case', 5]], '28759848', '0' ], [ [['presume laws are constitutional', 7]], '28747556', '0' ], [ [['has destroyed 15 to 25 houses', 7]], '28744868', '0' ], [ [['short answer is yes', 7]], '28746030', '0' ], [ [['opportunity to tell the real story', 7]], '28731764', '0' ], [ [['entirely respectable way to put off the searing constitutional controversy', 7]], '28723797', '0' ], [ [['point of my campaign is that big ideas matter', 9]], '28712293', '0' ], [ [['As the standoff dragged into a second day', 7]], '28687424', '0' ], [ [['French police stepped up the search', 17]], '28667224', '0' ], [ [['Seeking to elevate his candidacy back to a general', 8]], '28660934', '0' ], [ [['The tragic story of Trayvon Martin', 4]], '28647343', '0' ], [ [['Karzai will get a chance soon to express', 8]], '28630306', '0' ], [ [['powerful storms stretching', 8]], '28493546', '0' ], [ [['basic norm that death is private', 6]], '28413590', '0' ], [ [['songwriter also saw a surge in sales for her debut album', 6]], '28413590', '1', 'Watch music videos from Whitney Houston ', 'on Yahoo! Music', 'http://music.yahoo.com' ], [ [['keyword', 99999999999999999999999]], 'videoID', '1', 'overwrite-pre-description', 'overwrite-link-string', 'overwrite-link-url' ] ]

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Is acne contagious - Health and Fitness

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Wednesday, May 30, 2012

Video: Obama, Romney reach out to military members

>>> reaching out for the veteran vote in decision 2012 . earlier today mitt romney tried to connect with military members during an event in colorado. he told the crowd how 4 was touched by vets he met monday and how selflessly they gave themselves to their country.

>> i love the men and women of our armed forces and appreciate their sacrifice for this great nation. they give themselves something bigger than themselves, their country, their family.

>> during the commemorations yesterday, president obama had a special message to veterans especially those to the vietnam war from you kocame home and sometimes denny graded instead of selee greated. it was a national shame, a disgrace. that should have never happened. that's why here today we resolve that it will not happen again.

>> joining me is "the new york times" michael sheer who wrote about the military vote. nice to see you. as we show everybody the new gallup poll out yesterday 58% of vets support mitt romney , 34% obama . neither is military related, i mean in terms of being a veteran. how critical is the veterans' vote in securing that moving into 2012 ?

>> well, i think it's especially critical for obama because this is a president who has probably been more aggressive in his use of the military, you any the bin laden killing but also the use of drones, the pursuit of two wars, i mean so if there's ever a time that a democratic president should in theory be able to grab a bigger slice of those voters which have traditionally been republican voters, if you go back to past campaigns this that is moment. and yet that poll suggests he's got a lot of work to do.

>> president obama made a bold statement yesterday at arlington national cemetery about progress in iraq . take a listen to this.

>> for the first time in nine years, americans are not fighting and dying in iraq . we are winding down the war in afghanistan and our troops will continue to come home.

>> certainly that is a significant accomplishment, michael, on obama 's part, especially combined with the killing of osama bin laden . how can mitt romney compare to someone who has ended a war, has overseen the death of who would be the country's greatest enemy, that of bin laden ? is it like trying to compare apples and oranges ?

>> what mitt romney 's going to try to do is shift the conversation to other areas where he thinks he might be stronger. what you see mitt romney doing is, a, looking at benefits for veteran and ask whether veteran feel satisfied that the kind of things they're getting when they come home is what they need and of course a lot of veteran are dissatisfied, and then the other question is, one of sort of overall funding for the military. i mean you know mitt romney is really pushing hard on this idea that president obama wants to gut the military, wants to cut funding for all branches as part of the debt deal that he made last year, earlier this year. you'll have that conversation that mitt romney thinks that he can win and you know the question is whether those topics will be enough to kind of outweigh the accomplishments that the obama administration will claim.

>> as you talk about that yesterday mitt romney told the audience that he was speaking to that he wouldn't take the path to europe is taking and cut the size of our nation's military. take a listen to that.

>> the others to commit to preserve america as the strongest military in the world second to none with no comparable power anywhere in the world. we choose that course in america not so we win wars but so we can prevent wars.

>> talked about the defense cuts or the spending. this is a nation, we are a nation at war for over ten years now. how big of a platform do you think defense will be in the 2012 campaign and the conversations, the debates?

>> i mean looking i think it's part of it, i think that the -- it all fits in the broader conversation about the economy, the debt, the how much money that the government is spending. i think the obama campaign thinks that one of the things that gives them a stronger ground to stand on is this idea that people have sort of internalized the notion that the spending on wars in afghanistan and iraq over the last ten years has cost this country a lot sat home and kind of making it harder to grow out of the economic recession that we were in. so, i think the obama folks think they have that as an edge. mr. romney thinks that he can press the case that somehow president obama won't be as vigorous and enforcing kind of american interests abroad, and we'll see how that plays out over the course of the campaign.

>> forgetting the vet vote, is it all about their care what they need, going forward for their futures, betterment of their families the best jobs they can, the security that they find at home?

>> yeah. and i tell you that is a real key. and really focused on the men vets. there are female vets as well but the real struggle for obama is how to cut into mitt romney 's lead among men and here's a group if he can convince them that their economic fortunes are better off he might do well. you've seen mitt romney already talk about the economic problems for vets when they come back, having trouble finding a job, that's where he thinks he's going to go.

>> thank you. appreciate it.

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America's Got Talent Recap: Fire Burning

The America's Got Talent auditions continued to limp along Tuesday, with producers emphasizing that contestants had to go big or go home in St. Louis. It's unclear such an emphasis was placed in this city, but we seemed to have grabbed a very interesting cross-section of auditions from all over the United States.

I had my doubts when the first few auditions included the awful drummer/mom who played "I Will Survive" and lacked a band; a woman who crushes cans with her hands (instead of her boobs; a dancing chicken; and an awkward unicyclist/lassoer - but the auditions picked up. Too bad we didn't actually see many of them. On to a full recap!

Inferno
Spencer Horseman - After having a really poor escape artist last night we not only get a good looking escape artist in Spencer but a very dynamic performance that involved the right amount of danger. The fact that he had to fall to a mat to prevent his death was amazing. I predict that he'll automatically make it through to the live rounds and not have to do anything in Vegas just to prevent his accidental death. Some of his websites claim that he's also a "comedian" so I wonder if we'll ever see them.

Medium
Isaac Brown - You know when little children get to get away with saying whatever they want? Isaac had personality and it made up for how pitchy he was. I would love if he had his sisters and parents as backup dancers. Someone better call up Nickelodeon or Disney, because this kid needs to be part of a development package.

The Cut Throat Freakshow - I would have been impressed by the glass stepping woman if it wasn't for the viral video of the woman dancing on butter. For some reason, I would have watched butter woman much more than her. The eyelid lifting was similar to Captain and Maybelle from last season but with a lack of staging.

Mild
Tom Bonham - The slightly creepy puppet guy didn't have the Disney touch that made it family friendly. It was like watching a cracked out It's A Small World that a kindergarten created. While I'd love to see what he would have done in Las Vegas at least Howard and Sharon had the brains to say no.

"Little Ozzy" - We've had impersonators before, but I can't remember a little impersonator. The vocals weren't that bad at all, but I don't know where this goes. If this was a Vegas act, I'd love to see a full "Little Celebrity" group, even though that hugs the line of exploitation and taste.

Ron Christopher Porter Jr. - The queen-y guy was actually not a bad voice-actor. It's just not a Vegas act. I could see him do the opening to the winner's show, but it was a good video for a resume. He basically allowed Curtis the trash man to get another two minutes of camera time in front of America.

What was YOUR favorite act from the evening? Any potential winners here?

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Good Satellite tv for pc : For More Profit From This Segment | Submit ...

May 29th, 2012
Posted by JoneDirghayu

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Papa regarding Sat tv However it is . Taylor Howard the Stanford University or college Tutor along with previous Their astronauts researcher Emeritus, that is normally referred to as the actual ?Father associated with Satellite tv TV?. Howard made as well as created the very first satellite tv aerial along with device as part of his San Andreas, Los angeles storage inside 1976. Howard perished in the aircraft accident within Two thousand and two in the chronilogical age of 80. Currently Thirty-two a long time soon after Howards technology, it?s uncertain he might have created your huge step which satellite television technologies have produced.
Very first Satellite television : Sputnik
The 1st satellite television actually thrown into globe orbit had been Sputnik, that has been unveiled through the Ussr about Oct Some, ?57. The actual release associated with Sputnik started what?s typically called the actual ?space race?. The usa clarified with all the productive release involving Internet explorer My partner and i about Jan One particular, 1958. Later on which very same calendar year, Their astronauts was developed about October. One particular, 1958, to complete private investigation associated with room trip and also aeronautics.
Very first Marketing communications Satellite tv * Syncom 2
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Tuesday, May 29, 2012

INDIAN CORPORATE LAW: Depreciation and Sale-and-Lease-back ...

One of the most important deductions permissible under income tax law in relation to capital assets is depreciation. Under the general scheme of the Income tax Act, particularly section 32, depreciation is allowed to an assessee who is the owner of a capital asset used for the purposes of business. The criterion of ?ownership? is given a slightly more liberal scope under tax law. Assessees can make use of this relaxed understanding in structuring their transactions so as to gain the benefit of depreciation. One such device used is that of sale and lease back transactions. Such transactions often come under the scrutiny of revenue authorities as being not genuine. In this context, the question of claim of depreciation in the case of leasing transactions assumes importance. A couple of recent decisions have provided some measure of clarity in this regard.

In IndusInd Bank v. ACIT, ITA 6566/Mum/2002, a Special Bench of the Tribunal had to consider whether depreciation would be allowed to the lessor or to the lessee. The facts were that the assessee, a bank, entered into an agreement with another company under which the assessee was lease out a boiler to the company for a specific fixed period, subject to payment of lease rent. After the expiry of the period, the asset was to be sold to the company. The assessee bank claimed depreciation on the boiler. The Assessing Officer did not accept this claim on the ground that the transaction was merely a paper transaction. At best, according to the assessing officer, the transaction could be categorized as a finance lease and not an operating lease.

The Special Bench noted that in substance, a finance lease is akin to a loan from the lessor to the lessee. After examining the decision of the Supreme Court in Asea Brown Boveri v. IFCI 54 Taxman 512 (SC), and Association of Leasing & Financial Services Companies v. Union of India , and relying on Accounting Standard ? 19, the Special Bench noted the broad features of a finance lease as under (para 5.14 of the order of the Bench):

-???????? A finance lease is non-cancelable, and there is a fixed obligation on the lessee for payment of lease rent for the period of the lease. If the lease is terminated prematurely by the lessee, the lessor is entitled to recover his investment along with expected interest.

-???????? A finance lease is always for a fixed period. This period is calculated by taking into consideration the economic life of the asset; and is settled in such a way so as to fully recover the investment of the lessor together with interest.

-???????? The lessor is interested in the recoupment of his investment with interest in
the shape of rentals over the period of lease, and not really with the asset itself or its user.

-???????? The lessee bears the responsibility of costs of insurance, repairs, maintenance etc. The features of bailment are absent. An operating lease, on the other hand, has the features of bailment. In a finance lease, the responsibility of the lessee is not restricted only to taking ?as much care as a man of ordinary prudence would? as warranted under section 151 of the Contract Act, but extends beyond this threshold.

-???????? The equipment is chosen by the lessee, but the payment to the supplier is made by the lessor. Thus, the lessee chooses the assets, takes delivery, enjoys the
use of the asset, and bears the risks and costs of its wear and tear, taxes/charges in relation to the asset etc. The risks and rewards incidental to ownership vest with the lessee and not with the lessor. The lessor simply holds the title of asset by way of security for recouping the investment and interest.

The Special Bench further noted that in the case of an operating lease, a lessor can claim depreciation; however, in the case of a finance lease, only the lessee would be entitled to claim depreciation. The Tribunal noted that even for the purposes of tax law, ?In a lease transaction also there can be only one owner of the asset, that is, either the lessor or lessee and not both of them or either of them at their discretion. Whereas in the case of operating lease, it is the lessor who is the real owner of the asset, but in case of finance lease, it is the lessee who is to be regarded as the real owner of the asset. Ex consequenti only the lessor can claim depreciation in case of an operating lease and the lessee, as to who should be conferred the benefit of deprecation allowance.?

Further examining the terms of the agreement between the parties, the Special Bench held that the lease agreement was a paper transaction to cover up the reality. The bench noted, following the decision of the Supreme Court in Sundaram Finance Limited v. State of Kerala AIR 1966 SC 1178, ?The true effect of a transaction may be determined from the terms of the agreement considered in the light of the surrounding circumstances. In each case the Court has, unless prohibited by the statute, power to go beyond the document and to determine the nature of transaction, whatever may be the form of the document??

The Delhi High court also recently considered the question of when an agreement should be considered as a finance lease and when it should be considered as an operating lease. The Court reaffirmed that the question could not be decided by merely looking at the title, nomenclature or label given to the agreement: the terms and conditions of the Agreement are relevant but not conclusive. Surrounding circumstances can look at. The court followed Sundaram Finance, which in turn had relied on the following observation of Lord Esher MR in Re Watson ??When the transaction is in truth merely a loan transaction, and the lender is to be repaid his loan and to have a security upon the goods, it will be unavailing to cloak the reality of the transaction by a sham purchase and hiring. It will be a question of fact in each case whether there is a real purchase and sale complete before the hiring agreement. If there be such a purchase and sale in fact and afterwards the goods are hired, the case is not within the Bills of Sale Act. The document itself must be looked at as part of the evidence, but it is only part, and the Court must look at the other facts and ascertain the actual truth of the case.?

At the same time, these observations must not be treated as giving complete freedom to the revenue to ignore the wording of the contract between the parties: the Madras High Court recently clarified (CIT v. M/s High Energy Batteries, T.C. 579/2005, decided on 17^th April, 2012; a decision in the context of a reopening of assessment where the Revenue?s stance was that a sale and lease back transaction was not genuine), ?Given the freedom to enter into agreements with parties and guided by commercial considerations, even to invoke the theory of tax evasion, the Revenue must have sufficient material to draw an inference of what had been shown as an understanding on an agreement between the parties, is not, in fact, so.?

It is thus clear from these decisions that the distinction between operating leases and finance leases (clarified by the Supreme Court in ABB?s case) is relevant in income tax law as well, and suitable care needs to be taken in structuring transactions and drafting the agreements to avail of appropriate tax benefits.

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Nokia to release a Lumia Batphone for the hardcore Batman fan

The phone will feature a black polycarbonate body with a laser-etched Batman logo

What's next for a Batman fan who already has a?Batmobile and an?authentic-looking costume? Is it a?Batcave? A?mini-me sidekick? Or a... Batphone? A tweet by the official Nokia Twitter account revealed that the company is preparing a Batman-themed Lumia 900 phone for fans who can't get enough of the Caped Crusader.

While Nokia didn't divulge any more details about the device, U.K. website?Pocket-lint claims that the black Lumia with a laser-etched Batman logo will be an extremely limited release. Other than the Dark Knight-inspired design, though, it's expected to have the same features as a standard?Lumia 900.

No word yet on whether the phone will be available in the U.S. But it will hit Germany, France, and the U.K. at an unknown date, presumably before or around the time?The Dark Knight Rises arrives in theaters on July 20.

[via?Mashable]

This article was written by Mariella Moon and originally appeared on Tecca

Samsung Chromebox Series 3 review

More Info

What happens when you put a Chromebook in a box? You get a Chromebox, natch. Not content with launching its new Chromebook Series 5 550, Samsung's adding the Chromebox Series 3 -- a diminutive $329 desktop system -- to its lineup. Like its mobile cousin, the box runs version 19 of Chrome OS and features an Intel Core processor. Though it's clearly targeted at the education and enterprise markets, could Samsung's Chromebox be a compelling option for the Engadget reader? Can it transcend its cloud-based workstation origins? Is it a better choice than an entry-level Mac mini? Find out in our review after the break.

Gallery: Samsung Chromebox Series 3 review

Continue reading Samsung Chromebox Series 3 review

Samsung Chromebox Series 3 review originally appeared on Engadget on Tue, 29 May 2012 15:00:00 EDT. Please see our terms for use of feeds.

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Monday, May 28, 2012

Ann Coulter: MSNBC host who fallen argued soldiers aren?t heroes is a woman

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BLACK SABBATH Paranoid music review by Conor Fynes

'Paranoid' - Black Sabbath (9/10)

Barring the fact that the album was released a damned decade before metal was in full swing, Sabbath's 'Paranoid' was, and is as solid an album as they come. Although the self- titled debut may have had more of an immediate impact, Iommi and company would focus in on their doom innovation, a decision setting them further apart from the hordes of UK blues rockers. It's not often that an album is still relevant forty years after its release.

Considering how iconic 'Paranoid' is, it seems redundant to dwell on general information regarding the album. Suffice to say, taking into consideration that 1970 was the same year Led Zeppelin recorded 'II', Black Sabbath took a more downtuned, heavier approach to rock music. British rock was opening itself up to a more distorted sound in general, but Sabbath weren't afraid to sound ugly. A familiar blues style can be heard in Iommi's crunchy lead work, but the use of tritones, or 'evil' sounding riffs was what gave the band their then- unique take on rock music. The lyrical content somewhat fittingly either contends with the concept of war, or nightmarishly drug-fuelled adventures. As a respite from the doomy riffs, 'Paranoid' is fleshed out with some sounds of 60's era psychedelia, as best exemplified by the spacey, jam-oriented 'Planet Caravan'.

The first side of the album is a hit parade of some of the band's best-known tracks. 'War Pigs' sets up the rest of the album perfectly; a gloomy overture introducing Iommi's gritty guitar tone and some of the best riffs on the album. 'Paranoid' and 'Iron Man' are both instantly memorable tunes that have earned their due as rock radio staples. My favourite cut from the record would have to be 'Electric Funeral' however, opening the second side on an even darker note. From its signature psych-doom riff to lyrics about the apocalyptic existence of mutants in a post-nuclear city, it perfects the heavy darkness explored on the first side. The rest of 'Paranoid's later half doesn't feel quite as memorable as the first, however. The musical tightness never lets down, but 'Hand of Doom' and instrumental afterthought 'Rat Salad' feel a little less vital than the rest. Luckily, 'Fairies Wear Boots' wraps things up on a rocking note, closing with an epic lead melody that seems to foreshadow the future sound of Iron Maiden.

'Paranoid' is not quite perfect, but it's fairly close, especially considering that the sound of heavy metal was still so young. At the very least, it deserves its status as a classic. With memorable songwriting, evocative lyrics and some of the best riffs ever written, who could ask for more?

Conor Fynes | 5/5 | 2012-5-28

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Discovery expected to shift research direction in lupus and asthma

ScienceDaily (May 27, 2012) ? Newfound details of the immune system suggest a role for never-before-considered drug classes in the treatment of allergic and autoimmune diseases, according to a University of Alabama at Birmingham study published online May 27 in Nature Immunology.

The results advance the current understanding of the way the body's initial, vague reaction to any invading organism expands into a precise and massive counterattack. That expansion starts when a dendritic cell "swallows" a piece of any invader encountered, ferries it to the nearest lymph node and presents it there for notice by lymphocytes, the workhorse cells of the immune system.

According to the current model, dendritic cells first must encounter T lymphocytes in the paracortex, or T cell zone, within the node. Only there will the interaction enable lymphocytes to expand into an army of clones primed to attack the invader.

To the research team's great surprise, the data showed that, although immune response works this way during viral flu infections, it is not always the case. When the body is infested with parasitic worms, for instance, dendritic cells link with T cells near B lymphocytes, under the control of B cell-related signals and outside the T cell zone.

"Considering that diseases from asthma to lupus can occur because the system mistakenly ramps up the same types of T cell responses it normally uses against worms, our finding that B lymphocytes control the T cell/dendritic cell interactions that trigger such responses has important, practical implications," said Frances Lund, Ph.D., chair of the UAB School of Medicine's Department of Microbiology and corresponding author. "The field now has cause to look at several experimental and existing drugs known to interrupt B cell signals as potential treatments for diseases driven by T cells."

Study details

Before joining UAB in March 2012, Lund worked alongside Tim Mosmann, Ph.D., at the University of Rochester Medical Center. In 1986 Mosmann advanced his groundbreaking theory on the way the immune system decides which sets of immune cells are most effective against different invader types. According to his Th1/Th2 model, Th1 T helper cells were best against viruses because they helped invaded human cells self-destruct before viruses could turn them into virus factories. Th2 helper T cells were best against parasites because they helped the B cells mass produce antibodies that glommed onto and removed worms from the spaces between cells.

The current study found that B cells, as part of the Th2 response to worms, start pumping out a protein called lymphotoxin, which in turn signals nearby stromal cells to produce more of the chemokine CXCL13.

B cells are able to gather in B cell areas of lymph nodes in the first place because they express CXCR5 receptor proteins that sense and move toward higher concentrations of CXCL13. The team discovered that a set of dendritic cells also begins expressing CXCR5 during a worm infection.

With B cells and activated dendritic cells gathered near B cells, T helper cells next must join the party if the immune response is to expand. While T cells dump into lymph nodes at many points, only those that happen to enter near B cells, and to bump into CXCR5-expressing dendritic cells, drive the response to worms forward, according to the authors.

The authors also believe such interactions trap T cells near the B cell area and that proximity determines the kind of cells they becomes next. Those receiving the strongest signals become the T helper follicular cells that B cells must partner with to produce antibodies specific to the current pathogen. Those getting weaker signals become Th2 effectors that travel back to the infection site to cause the histamine release and intestinal muscle contractions that help to expel worms.

Though vital to effective immune responses to worms, T helper follicular cells and Th2 cells have a dark side. For example, T helper follicular cells in some cases inappropriately help B cells produce high affinity "auto" antibodies that recognize the body's own cells as foreign and can destroy the kidneys of lupus patients and the joints of patients with rheumatoid arthritis.

In other cases, Th2 cells respond to allergens in the lung like house dust mites because the mites look like worms to the immune system and the confused Th2 cells respond to the allergen as they would to a worm. This mistaken recognition causes histamine release and bronchoconstriction in the lungs, two of the major clinical symptoms of asthma.

"We know of experimental biologics that interrupt the ability of B cells to give off lymphotoxin and prevent the development of helper Th2 cells and T helper follicular cells," Lund said. "Could such antibody-based treatments be useful against some autoimmune diseases and asthma? We think so, but time and further studies will tell."

Along with Lund, Troy Randall, Ph.D., the Claude Bennett Scholar in the UAB Department of Medicine's Division of Clinical Immunology and Rheumatology, and UAB post-docs Beatriz Le?n, Ph.D., and Andr? Ballesteros-Tato, Ph.D., made major contributions to the work. Also making important contributions were Jeffrey Browning at Biogen Idec and Robert Dunn at the Pfizer Centers for Therapeutic Innovation (formerly at Biogen Idec). The study was supported by the National Institute of Allergy and Infectious Diseases.

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The above story is reprinted from materials provided by University of Alabama at Birmingham, via Newswise.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.

Journal Reference:

Beatriz Le?n, Andr? Ballesteros-Tato, Jeffrey L Browning, Robert Dunn, Troy D Randall, Frances E Lund. Regulation of TH2 development by CXCR5 dendritic cells and lymphotoxin-expressing B cells. Nature Immunology, 2012; DOI: 10.1038/ni.2309

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

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Sunday, May 27, 2012

Summit 111-5 Mosquito Dunks, 20-Pack | internetproductsuperstore ...

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Summit 111-5 Mosquito Dunks, 20-Pack

Kills mosquitoes before they?re old enough to bite
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Kills mosquitoes before they?re old enough to bite. The Mosquito Dunks are America?s best selling home owner mosquito control product. The only product with BTI, a bacteria toxic only to mosquito larvae, that lasts 30-day and treats 100-square feet of surface water. Non-toxic to all other wildlife , pets, fish, and humans. Simply apply Mosquito Dunks to any standing water, or water garden. Kills within hours lasts for 30-day or more. Labeled For Organic Gardening by the USEPA. Highly effective low impact product.

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Saturday, May 26, 2012

Himachal Tour A Lovely Romantic Honeymoon Tour Of India

Himachal Pradesh has long been a dream destination for me. And off course there are enough reasons to be it my favourite destinations. Rich flora and fauna, snow-capped mountain peaks, apple orchards, beautiful valleys with wild flowers, meadows of wild flowers, wonderful waterfalls, lovely lakes, picturesque hill resorts with well accommodation, and adventure & sports, etc are enough reason to make it favourite travel destinations of India. Himachal Pradesh is predominantly known for scenic beauty, cool & pleasant environments and adventure and sports. I have traveled several tourist destinations of India but could find so much charm and beauty of nature as Himachal has to offer its visitors.

The capital hill station of the State, Shimla, was referred to as the Summer Hill station of India during the British times. The hill station is well known for its exclusive architecture, the famous shopping mall and the dense forests which are rich in varied kinds of flora and fauna. The major tourist spots of Shimla are The Mall, the Chadwick hill, The State Museum, the Jakhu Hill and the Christ Church. With the Himachal Tour Package, in hand, you can also get to visit Dalhousie, Chail, Chambal, Kasauli and Dharamshsla. The best way to have a complete Himachal Tour is by going on a ride in the famous Toy Train, which offers you a view of the snow peaked mountains, the lush green dense forests and the varied topography.

The term Himachal Pradesh literally means 'the state covered with snow'. It is a hill station which is favored by honeymooners, holiday makers and adventure buffs. This land boasts of around 32 wildlife sanctuaries, 2 National Parks and 3 Games Reserves. Himachal Tour, offers amazing opportunities for adventure sports such as trekking, mountaineering, skiing, swimming, camping, river rafting, kayaking, sailing, canoeing, paragliding, surfing and rowing. You can explore the mesmerizing attractions of this state on Jeep Safari, Bike safari, river safari and even Yak safari.
This land is also known as the land of Gods. Some of the famous pilgrimage centers of the country are located in this state. From ancient temples to beautiful monasteries and gurud waras, this destination has several religious centers. There are great mythological stories associated with some of the temples.
Himachal Pradesh is dotted with several enchanting destinations which are a big hit with tourists. Shimla, Manali, Kullu, Spiti, Kinnaur, Kasauli, Kufri, Solan, Palampur, Narkanda and Bilaspur are the most famous tourist destinations of Himachal Pradesh Tourism.
Shopping is something which should not be missed while you are in this wonderful destination. A variety of handicrafts are available in its colorful markets. The woolen shawls, rugs, carpets and Kangra style of paintings are the most famous handicrafts of this state. A variety of wooden items are also available here such as ladles, bedsteads, boxes, cradles etc.
You can choose from a variety of Himachal Pradesh tour packages depending on your budget, interest and number of days you have in hand. From adventure sports tour to scenic beauty tours, you will get amazing variety here.
Just imagine yourself amidst an environment where snow-covered mountain peaks are reaching up to the sky, apple orchards in full bloom, valleys carpeted with flowers, lovely streams gushing down and rosy-cheeked people greeting you with a smile. Such is the charm of Himachal Pradesh. Just let yourself loose in its staggering natural beauty and enjoy every bit of it. You are bound to forget all your day to day worries and go back home completely refreshed.

About the Author:
vinod Sharma is a traveler who likes to share his experiences. All the articles published by him will help you understand India better and answer all your holiday queries regarding, Himachal Tour Package, Find tourist info on travel packages, travel destination, and much more.

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Times-Picayune to cut paper to 3 days a week

NEW ORLEANS (AP) ? The Times-Picayune, one of the nation's oldest newspapers, will no longer offer print editions seven days a week and instead plans to offer three printed issues a week starting in the fall. The change means New Orleans would become the largest metro area in the nation without a daily newspaper in the digital age.

The changes announced Thursday were combined with similar moves at three major Alabama daily newspapers also owned by the Newhouse family group's Advance Publications. The Birmingham News, the Press-Register in Mobile and The Huntsville Times will switch to publishing three days a week as part of a new focus on online news. At all four papers, there will be unspecified staff cuts. All four papers will continue to publish continuously on their websites, and online access will remain free.

Newspapers have struggled in recent years as consumers increasingly get their news online. Print advertising declined as the economy went into recession, and newspapers have yet to learn how to make online advertising as profitable as its printed counterpart.

"For us, this isn't about print versus digital, this is about creating a very successful multi-platform media company that addresses the ever-changing needs of our readers, our online users and our advertisers," said Advance Publications' president of local digital strategy, Randy Siegel, in an interview with The Associated Press. "This change is not easy, but it's essential for us to remain relevant."

Siegel didn't say how much money the reduced print runs in Louisiana and Alabama would save, nor how many staff members would be laid off or hired in the new online units.

"To get good quality information is not cheap," said Jennifer Greer, chair of the journalism department at the University of Alabama. "What you are seeing is people trying to figure out a business model that works in a digital age."

The decision was met with sadness by some residents in New Orleans, where The Times-Picayune won a Pulitzer Prize for its coverage of Hurricane Katrina in 2005. Staffers continued reporting despite being forced out of the newspaper's offices amid widespread flooding and power outages.

The storm drove away thousands of residents, some of whom never came back. The city ? and its newspaper ? struggled to recover in the years since.

The paper was a lifeline for the Southern, working-class city, providing government announcements, obituaries, Carnival and scoops on local corruption, said Cheron Brylski, a 53-year-old New Orleans-based political consultant. Not having the paper every day is like losing a sports team, she said.

"Where is New Orleans headed since Katrina? This is not something that helps our recovery," she said.

The papers in Alabama also have long histories. The Mobile paper has roots to 1813 with the founding of the Mobile Gazette and became a daily in 1832, according to a history of the publication on al.com. And in 2007, the Birmingham News won a Pulitzer Prize for a series on corruption in Alabama's two-year college system.

Birmingham News employees were told during morning meetings that longtime Editor Tom Scarritt will retire this fall when the new companies are created, according to two reporters who spoke on condition of anonymity because they were not authorized to speak publicly about the changes for the company.

In New Orleans, a new company, the NOLA Media Group, would be created to oversee both The Times-Picayune and its affiliated website, NOLA.com.

The announcements mirror changes Advance Publications made in Michigan. In 2009, the company shut the Ann Arbor News but created AnnArbor.com, a news website that still publishes print editions on Thursday and Sunday.

In February, it launched the MLive Media Group, which runs MLive.com, to focus its efforts in Michigan digitally. Meanwhile, all of its eight other newspapers in the state offer three days of home delivery with newsstand sales from three to seven days a week.

Newspaper analyst Ken Doctor, who writes the Newsonomics blog, said the company is trying to hold on to declining print ad revenue for a few more years, and expects Advance to eventually cut print runs at its other newspapers in New Jersey, Oregon, Ohio and elsewhere. The company owns The Oregonian in Portland, Ore.; The Plain Dealer in Cleveland; and The Star-Ledger in Newark, N.J.

"It's a big bet to retain profitability and hope that in the shock therapy, there are profits on the other end," he said.

Print circulation has been dropping steadily over the years at the four newspapers affected by Thursday's announcement, according to the Audit Bureau of Circulations. On average, the four papers' circulation in the half year through March fell about 6 percent from a year ago.

Nonetheless, the Times-Picayune remains one of the nation's most successful newspapers. Of the top 50 large-sized markets, the newspaper has the highest rate of readership of its daily edition in the U.S., according to Austin, Texas-based Scarborough Research, a firm that tracks the industry.

The Times-Picayune's average paid circulation was 133,557 in the six months through March, down 49 percent compared to March 2005, a few months before Hurricane Katrina hit.

The Birmingham News' circulation of 103,729 is down 29 percent from five years ago; the Press-Register's of 82,088 is down 18 percent; and The Huntsville Times' of 44,725 is down 15 percent.

Die-hard supporters and even Mayor Mitch Landrieu pledged to make sure the newspaper remained a part of New Orleans culture.

"Through wars and floods, the 'Aints and a Saints Super Bowl victory, the TP has been and remains an integral part of our daily routine and our culture," Landrieu said.

Anne Milling, a longtime member of the advisory board to The Times-Picayune, said an online-focused model wouldn't work in New Orleans. She said she and other supporters were exploring bringing in new owners committed to a daily paper, or even starting a new daily publication.

"We always do things differently," she said. "It's part of our tradition: You wake up with a cup of chicory coffee and read the newspaper."

___

Business Writer Ryan Nakashima in Los Angeles, Phillip Rawls in Birmingham, Ala., and Janet McConnaughey in New Orleans contributed to this report.

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